Cell Line Development Scientist

<section style="font-size: 10.0pt; font-family: 'Tahoma',sans-serif;"> <div> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">(ID: 2026-3798)</span></p> <br> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Axle</strong> is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).</span></p> </div> <br> <div> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Axle</strong> is seeking a <strong><em>Cell Line Development Scientist </em></strong> to join our vibrant team at the National Institutes of Health (NIH) supporting the <strong>National Institute of Allergy and Infectious Diseases (NIAID) located in Gaithersburg, MD.</strong></span></p> </div> <br> <div> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Benefits We Offer:</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">100% Medical, Dental &amp; Vision Coverage for Employees</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Paid Time Off and Paid Holidays</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">401K match up to 5%</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Educational Benefits for Career Growth</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Employee Referral Bonus</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Flexible Spending Accounts:</span> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Healthcare (FSA)</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Parking Reimbursement Account (PRK)</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Dependent Care Assistant Program (DCAP)</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Transportation Reimbursement Account (TRN)</span></li> </ul> </li> </ul> </div> <div class="ck-content" style="font-family: Segoe UI; font-size: 11pt;" data-wrapper="true"> <p style="margin: 0;">&nbsp;</p> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Position Overview</strong></span></p> <p style="margin: 0; text-align: start;">&nbsp;</p> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">The Cell Line Development Scientist will support the planning and execution of research experiments within the laboratory’s overall research program. The role focuses on developing stable cell lines for vaccine and therapeutic protein candidates, including monoclonal antibodies, recombinant proteins, and virus-like particles. It covers the full cell line development process, from plasmid preparation and transfection through clone selection, fed-batch analysis, and stability studies. The role also includes small-scale process development, laboratory equipment support, documentation, and project coordination with project leads. A Master’s degree is required.</span></p> <p style="margin: 0; text-align: start;">&nbsp;</p> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Certifications &amp; Licenses</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="eeff5d2a47d8d8543bcc460e1dad24fe0"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Master of Science (M.S.) in Biological Science</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e2a82f179d4994010d6f72ea2adadaa33"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Bachelor of Science (B.S.) in Biological Sciences</span></p> </li> </ul> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Field of Study</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e784c3c44b59c203f5dc1eecafaaec944"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Biochemical Sciences</span></p> </li> </ul> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Software</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="ebe1e6a60db468198db9241d38aaf65e3"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Prism, FlowJo, Word, PowerPoint, Excel</span></p> </li> </ul> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Skills</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="eacb5986678d813535fc83bbc76a0a202"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Monoclonal antibody and/or vaccine production</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="ef1f17b27a1fc203693c098707472fb5d"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Technical reports, standard operating procedures, and data presentations</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="eecb9eb5801cf81826c1c913db84526b4"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Cell line engineering technologies, including cell counting, high-throughput transfection, single-cell cloning, and flow cytometry</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="eae338313f24903295d2a6f02ad705485"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Aseptic technique and mammalian cell culture</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e6deed19029a375066a06ff5c276c4e9d"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Broad knowledge of state-of-the-art principles and theory</span></p> </li> </ul> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Deliverables</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="ece986a0afb816346ce937dd5da3452bc"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Provide reports (Ad-Hoc)</span></p> </li> </ul> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Statement of Work Details</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e0ed7da6a70d3d09f2b50a9c079966931"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Contribute to the development of stable cell lines for vaccine and therapeutic protein candidates, including monoclonal antibodies, recombinant proteins, and virus-like particles.</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="eeb6dbebcfa7a08d004bd9df9ea9c77d1"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Independently execute each step of the cell line development process: transfection, pool generation, single-cell cloning, clone expansion in static culture plates and shake flasks, fed-batch analysis, and clone stability studies.</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e78b2630b736c70d98622eef07c460fb7"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Participate in cell line development platform design, optimization, and cycle-time reduction studies, including methods for clone selection, expansion, ranking, and characterization.</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e94189bde82e5edc73f4c66a2b239c53b"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Generate stable pools and perform transient protein production to supply reagent-grade material.</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e83d251848a53322a5099d7dc8cec3035"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Maintain, support, and track maintenance for core laboratory equipment, including the ViCell BLU cell counters used on all cell line development projects to count cells during passaging and fed-batch production.</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e2253728aa6bdb55c5b88da47405a37ca"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Support the planning and execution of research experiments within the laboratory’s overall research program.</span></p> </li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;" data-list-item-id="e6f33b88c1a4dcb7049d3092ac37e1276"> <p style="margin: 0; text-align: start;"><span style="font-family: tahoma, arial, helvetica